Retinoids Help Normalize KeratinizationAlthough the mechanism by which topical and systemic retinoids help restore acne follicles to a healthy state is unknown, it has been well demonstrated that they normalize keratinization within the infundibular region of the follicle, so that shed follicular cells slough to the surface of the skin rather than clump together and obstruct the pores.After exposure to retinoids, follicular cells actually turn over more rapidly than they would in a pre-acne state.Retinoic acid has a high affinity for the gamma retinoid receptors, which are believed to be integral to the pathogenesis of acne.In addition to their ability to reverse abnormal keratinization within the follicle, the topical retinoids - especially adapalene (Differin®), a naphthoic acid derivative - may have anti-inflammatory properties and thus may address two factors involved in the development of acne.
Pustules are similar to whiteheads. The difference is that they appear inflamed and red - usually with a yellow center. Again a benzoyl peroxide product works well.
Acne is the skin curse of many people around the world; but there are now many treatments available which can help the condition so it is more bearable. A great deal of money is being spent researching the condition; the result of this effort is new, more effective, treatments are becoming available. There are a broad range of acne skin care products available:
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